A machine was immersed in a translucent yellow slimy shallow bucket and pulled out a life-size hand. Can you imagine this scene happened in real life?
The hand made using the traditional 3D printing method takes six hours. Engineers at the University of Buffalo showed people the progress in 3D printed human tissues and organs. This biotechnology can ultimately save countless lives lost due to the shortage of donor organs.
The co-lead author of the study, Associate Professor Zhao Ruogang, said: “The technology we have developed is 10 to 50 times faster than industry standards and can handle large sample sizes that were previously difficult to achieve.” Biomedical Engineering.
This work is described in a study published in the journal Advanced Medical Materials on February 15.
It centers on a 3D printing method called stereolithography and jelly-like materials called hydrogels, which are used in tissue engineering to make diapers, contact lenses, and stents.
The latter application is particularly useful in 3D printing, which is why the research team spends most of their energy optimizing to achieve its incredibly fast and accurate 3D printing technology.
“Our method can quickly print centimeter-sized hydrogel models. It can significantly reduce part deformation and cell damage caused by long-term exposure to environmental stresses common in traditional 3D printing methods,” the research’s other common goals Yes: Lead author, Zhou Chi, PhD, associate professor of industrial and systems engineering.
The researchers said that the method is particularly suitable for printing cells with embedded blood vessel networks. This is an emerging technology that is expected to become a core part of the production of 3D printed human tissues and organs.
The first authors of the study include a former UB student, Dr. Nanditha Anandakrishnan, a postdoctoral researcher at the Icahn School of Medicine at Mount Sinai, and Dr. Hang Ye, a research scientist at SprintRay Inc..
UB’s other co-authors are from the Department of Biomedical Engineering, a joint project between the School of Engineering and Applied Sciences and the Jacobs School of Medicine and Biomedicine; the Department of Industrial and Systems Engineering; the Department of Chemical and Biological Engineering; and Jacobs The school’s medical department.
Other research co-authors are from the VA Western New York Healthcare System; the Department of Cellular Stress Biology at Roswell Park Comprehensive Cancer Center; and the Department of Biomedicine and Chemical Engineering at Syracuse University.
This work was funded by the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health. The UB School of Engineering and Applied Sciences and the Jacobs School of Medicine and Biomedicine provided additional funding.
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